Nuclear Condensation during Mouse Erythropoiesis Requires Caspase-3-Mediated Nuclear Opening
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چکیده
منابع مشابه
Nuclear substructure reorganization during late-stage erythropoiesis is selective and does not involve caspase cleavage of major nuclear substructural proteins.
Enucleation, a rare feature of mammalian differentiation, occurs in 3 cell types: erythroblasts, lens epithelium, and keratinocytes. Previous investigations suggest that caspase activation functions in lens epithelial and keratinocyte enucleation, as well as in early erythropoiesis encompassing erythroid burst-forming unit (BFU-E) differentiation to proerythroblast. To determine whether caspase...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2016
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2016.02.001